NFL Thursday Night Football best bets Week 4

Week 4 of the NFL season gets Thursday night underway with the Pittsburgh Steelers taking on the Cleveland Browns . There are several player props worth targeting in this AFC North matchup, with Jaylen Warren , Denzel Boston, Pat Freiermuth , and Harold Fannin Jr. all presenting intriguing opportunities.

Sep 13, 2026; Pittsburgh, Pennsylvania, USA; Pittsburgh Steelers running back Jaylen Warren (30) runs during the fourth quarter against the Atlanta Falcons at Acrisure Stadium. Mandatory Credit: Charles LeClaire-Imagn Images Credit: IMAGN IMAGES via Reuters Connect (Reuters)

Jaylen Warren over 59.5 rushing yards is one of the best bets to consider Thursday night. Warren has already rushed for 216 yards on 38 carries through three games, averaging an impressive 5.7 yards per carry.

Cleveland has allowed 120.3 rushing yards per game through the first three weeks, creating a favorable matchup for Warren. His efficiency has also been one of the biggest positives for Pittsburgh's offense early this season.

If Warren continues to receive the majority of Pittsburgh's rushing workload, 60 yards is a very attainable number.

Sep 20, 2026; Tampa, Florida, USA; Tampa Bay Buccaneers cornerback Benjamin Morrison (21) defends against Cleveland Browns wide receiver Denzel Boston (12) during the second half at Raymond James Stadium. Mandatory Credit: Kim Klement Neitzel-Imagn Images Credit: IMAGN IMAGES via Reuters Connect (Reuters)

Denzel Boston over 35.5 receiving yards is another prop that stands out. Boston has nine receptions for 195 yards through three games, averaging an incredible 21.7 yards per reception.

That big-play ability makes this number particularly appealing. Boston doesn't need a massive target total to clear 35.5 yards, as one or two explosive receptions could put him over the number.

Pittsburgh's defense has been solid against the pass, but Boston has already demonstrated the ability to produce regardless of matchup.

Pat Freiermuth over 28.5 receiving yards

Sep 13, 2026; Pittsburgh, Pennsylvania, USA; Pittsburgh Steelers tight end Pat Freiermuth (88) celebrates with quarterback Aaron Rodgers (8) after a touchdown during the second quarter against the Atlanta Falcons at Acrisure Stadium. Mandatory Credit: Charles LeClaire-Imagn Images Credit: IMAGN IMAGES via Reuters Connect (Reuters)

Pat Freiermuth over 28.5 receiving yards is another strong option. Freiermuth has 11 receptions for 108 yards through three games, giving him an average of 9.8 yards per reception.

That means Freiermuth needs only a handful of catches to get past this number. He has also already found the end zone once this season, showing that he remains involved in Pittsburgh's passing attack.

With the Browns presenting a divisional matchup where short and intermediate throws could be important, Freiermuth should have opportunities to make an impact.

Sep 27, 2026; Cleveland, Ohio, USA; Cleveland Browns tight end Harold Fannin Jr. (44) makes a catch for a touchdown against the Carolina Panthers during the fourth quarter at Huntington Bank Field. Mandatory Credit: Ken Blaze-Imagn Images Credit: IMAGN IMAGES via Reuters Connect (Reuters)

Harold Fannin Jr. over 4.5 receptions is another intriguing play. Fannin has established himself as an important part of Cleveland's passing attack and enters Thursday night with a 4.5-reception line.

The rookie tight end has shown the ability to pile up receptions, and his role gives him a path to reaching five catches even without a huge yardage performance.

Cleveland could also rely on Fannin underneath against Pittsburgh, making the reception total particularly interesting.