College GameDay picks Week 5's biggest games

Week 5 of the college football season is here, and ESPN's premier preview show is back to pick college football's most intriguing games.

This week, "College GameDay" was in Iowa City, Iowa, for the top-25 Big Ten showdown between the No. 14 Iowa Hawkeyes and the No. 6 Ohio State Buckeyes at Kinnick Stadium. Saturday was the 3rd time College GameDay has originated from the University of Iowa , and the first time since Sept. 30, 2006, when the Hawkeyes hosted Ohio State.

This week, the usual lineup of Rece Davis, Kirk Herbstreit, Desmond Howard, Pat McAfee, and former Alabama head coach Nick Saban made their picks for this week's biggest games, with Caitlin Clark serving as this week's celebrity guest picker.

Clark won the Big Ten Player of the Year award three times as a point guard for the Iowa Hawkeyes after averaging 28.4 points, 8.2 assists, and 7.1 rebounds per game over her four-year career from 2020-24. She later became the No. 1 overall pick in the 2024 WNBA Draft and is now one of the league's most recognizable faces with the Indiana Fever.

How did the College Gameday crew forecast this week's top games? Here's a look at this week's picks for Week 5 of the college football season.

Kirk Herbstreit: No pick due to calling the game on ABC

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