NFL Week 4 injury roundup: Lamar Jackson, Ja’Marr Chase and Saquon Barkley among stars raising Week 5 concerns

The NFL’s Week 4 injury list could have a real effect on several teams heading into Week 5. Ja’Marr Chase is in concussion protocol, Saquon Barkley is dealing with a hamstring injury and Lamar Jackson has an ankle issue that has already left him in a walking boot. Those are not the only concerns. Kansas City lost Tyquan Thornton to a serious ankle injury, Arizona’s Paris Johnson Jr. is out for the season, and Green Bay’s Edgerrin Cooper also suffered a season-ending Achilles tear. The next few days will be important as teams wait for updates on key players.What is the latest on Ja’Marr Chase and Saquon Barkley?Chase’s injury could be particularly costly for Cincinnati. The Bengals fell to 2-2 after losing to Jacksonville, then watched their biggest offensive weapon leave with a concussion. Chase did not return after being evaluated and is now in the NFL’s concussion protocol.His availability for Week 5 will depend on how he progresses through the league’s steps. Cincinnati also has another concern at receiver. Tee Higgins suffered an adductor injury and is considered day-to-day, leaving the Bengals potentially short on their top two pass catchers.Philadelphia has its own offensive issue with Barkley. The Eagles running back suffered a hamstring injury against the Los Angeles Rams and is now considered week-to-week. His status for Week 5 remains unclear.Barkley’s workload has already drawn attention this season, so the timing of the injury adds another layer to Philadelphia’s situation. The Eagles will need to be careful with a player whose explosiveness is central to their offense.Is Lamar Jackson expected to play in Week 5?Baltimore has received some relief on that front, at least for now. Jackson suffered an ankle injury during the Ravens’ Week 4 win over Tennessee and was seen wearing a walking boot afterward.That image naturally raised concern about the quarterback’s availability. However, the injury is currently considered day-to-day. That gives Baltimore some hope that Jackson will avoid an extended absence, although his practice participation will likely be closely watched throughout the week.The Ravens have started the season strongly, making Jackson’s health especially important. Even a short absence would force Baltimore to adjust an offense that is built heavily around his ability to create plays with both his arm and legs.Which other NFL stars suffered significant injuries?Kansas City faces a more serious situation with Thornton. He scored twice against Las Vegas before suffering a dislocated left ankle late in the game. His ankle was reset, but he is out indefinitely while further testing is completed. Rashee Rice also left that game with a hamstring injury.Arizona has lost Johnson for the rest of the season because of a biceps injury. Green Bay will also be without Cooper after he tore his Achilles tendon.Denver received better news on Patrick Surtain, whose ankle injury is considered short-term. Other Week 4 injuries included Antoine Winfield Jr.’s rib issue, Jonathan Greenard’s ankle injury, Kyle Juszczyk’s ankle problem, Ladd McConkey’s foot injury, Joe Alt’s neck injury and DJ Moore’s shoulder issue.Stay updated with the latest Asian Games 2026 news, check the Asian Games medal tally and complete Asian Games schedule.Get the latest Sports News and Live updates. Download the TOI app.