ESPN 'College GameDay' predictions for Week 4

Week 4 of the 2026 college football season is here, and that means ESPN's "College GameDay" was back in full force to preview all of Saturday's action. With a ranked matchup in the SEC, they made the choice to head to Knoxville, Tennessee, to watch the Texas Longhorns plays the Tennessee Volunteers .

It is the SEC opener for both programs, who each started the year 3-0. While Texas already has a win over the Ohio State Buckeyes , this will be their first road game of the season. It is also Arch Manning 's first time playing in Neyland Stadium, creating an interesting dynamic for his uncle Peyton Manning .

The usual crew of Rece Davis, Nick Saban, Kirk Herbstreit, Desmond Howard, and Pat McAfee were joined by guest picker Johnny Knoxville to pick the top games of the weekend. He is from Knoxville, Tennessee, and is a longtime supporter of the Vols.

Here is a look at all of their picks for the top games in Week 4 of the season, including the Florida Gators vs. Ole Miss Rebels, Michigan Wolverines vs. Iowa Hawkeyes , and more.

Boise State Broncos vs. Western Michigan Broncos

Oklahoma State Cowboys vs. West Virginia Mountaineers

Mississippi State Bulldogs vs. Missouri Tigers

Tennessee Volunteers vs. Texas Longhorns