Week 4 high school football schedule for San Antonio-area teams

More than a handful of San Antonio-area districts have begun district play or are beginning their slate this week. By next week, most districts will have joined the party, including District 28-6A, which has a district-wide open week this week.

There are many exciting games this weekend, including the Game of the Week, which features Warren and Harlan in a clash of styles , with both teams looking for an inside track to contend for the 29-6A crown.

Here is the Week 4 high school football schedule for San Antonio-area teams.

Holmes (1-2, 0-1) vs. O'Connor (1-1, 0-0) 7 p.m., Gustafson Stadium O'Connor leads series 21-5 Most recent meeting: 2025, O'Connor: 52-28 Last win for Holmes: 2021 (39-14)

Seguin (0-3, 0-1) vs. Bastrop Cedar Creek (2-1, 0-1) 7 p.m., Bastrop Memorial Stadium Seguin leads series 1-0 Most recent meeting: 2020, Seguin: 48-2 Last win for Bastrop Cedar Creek: None

Highlands (0-3, 0-1) vs. Edison (0-3, 0-1) 7 p.m., Alamo Stadium Highlands leads series 28-14-1 Most recent meeting: 2025, Highlands: 65-6 Last win for Edison: 2024 (27-14)

Harlandale (1-2, 1-0) vs. Lanier (2-1, 1-0) 7 p.m., SAISD Complex Harlandale leads series 21-3 Most recent meeting: 2023, Harlandale: 44-0 Last win for Lanier: 1976 (34-12)

New Braunfels (1-2) vs. Cedar Park (3-0) 7 p.m., Gupton Stadium First meeting

Victoria West (3-0) vs. SA Veterans Memorial (2-1) 7 p.m., Rutledge Stadium Victoria West leads series 2-0 Most recent meeting: 2025, Victoria West: 13-7 Last win for SA Veterans Memorial: None

Clemens (3-0, 0-0) vs. Judson (0-2, 0-0) 7:30 p.m., Rutledge Stadium Judson leads series 22-13 Most recent meeting: 2025, Judson: 31-28 Last win for Clemens: 2023 (24-17)

New Braunfels Canyon (2-1, 0-0) vs. East Central (1-2, 0-0) 7:30 p.m., Hornet Stadium New Braunfels Canyon leads series 8-6-1 Most recent meeting: 2025, New Braunfels Canyon: 28-7 Last win for East Central: 2021 (34-17)

Wagner (1-1, 0-0) vs. Steele (1-1-1, 0-0) 7:30 p.m., Lehnhoff Stadium Steele leads series 8-0 Most recent meeting: 2021, Steele: 28-21 Last win for Wagner: None

Pieper (1-2, 0-0) vs. San Marcos (0-3, 0-0) 7:30 p.m., Rattler Stadium First meeting

Warren (2-1, 1-0) vs. Harlan (2-1, 1-0) 7:30 p.m., Farris Stadium Harlan leads series 6-0 Most recent meeting: 2025, Harlan: 49-7 Last win for Warren: None

Stevens (0-3, 0-1) vs. Taft (2-1, 0-1) 7:30 p.m., Gustafson Stadium Stevens leads series 11-7 Most recent meeting: 2025, Stevens: 42-37 Last win for Taft: 2024 (28-27)

Laredo Johnson (2-1, 0-0) vs. Southwest Legacy (2-0-1, 0-0) 7:30 p.m., Legacy Stadium Laredo Johnson leads series 2-0 Most recent meeting: 2019, Laredo Johnson: 17-16 OT Last win for Southwest Legacy: None

Southwest (0-2, 0-0) vs. Del Rio (1-2, 0-0) 7:30 p.m., Levermann Stadium Del Rio leads series 6-4 Most recent meeting: 2017, Southwest: 20-0 Last win for Del Rio: 2016 (20-14)

Boerne Champion (3-0, 1-0) vs. Kyle Lehman (1-2, 0-1) 7:30 p.m., Shelton Stadium Boerne Champion leads series 4-0 Most recent meeting: 2023, Boerne Champion: 35-23 Last win for Kyle Lehman: None

Smithson Valley (2-0, 1-0) vs. Manor (2-1, 1-0) 7 p.m., Manor Athletic Complex First meeting

Jefferson (1-2, 0-1) vs. Burbank (0-2, 0-0) 7 p.m., Alamo Stadium Jefferson leads series 30-13 Most recent meeting: 2025, Jefferson: 42-25 Last win for Burbank: 2024 (27-7)

Sam Houston (2-1, 1-0) vs. McCollum (1-2, 1-0) 7 p.m., Harlandale Stadium Sam Houston leads series 9-0 Most recent meeting: 2023, Sam Houston: 28-22 Last win for McCollum: None

Houston St. Pius X (1-2, 0-0) vs. Antonian (1-1, 0-0) 7 p.m., John Ferrara Field Antonian leads series 7-5 Most recent meeting: 2025, Antonian: 35-26 Last win for Houston St. Pius X: 2018 (55-14)

Houston St. Thomas (2-2, 0-0) vs. Central Catholic (3-1, 0-0) 7 p.m., Benson '66' Stadium Houston St. Thomas leads series 21-9 Most recent meeting: 2025, Houston St. Thomas: 45-3 Last win for Central Catholic: 2021 (35-31)

Holy Cross (1-2, 0-0) vs. Bay Area Christian (4-0, 0-0) 7 p.m., Bronco Field Holy Cross leads series 2-0 Most recent meeting: 2023, Holy Cross: 66-6 Last win for Bay Area Christian: None

Somerset (1-1) vs. Boerne (3-0) 7 p.m., Boerne ISD Stadium Boerne leads series 21-17-1 Most recent meeting: 2023, Boerne: 31-7 Last win for Somerset: 2012 (49-6)

Floresville (2-1) vs. New Braunfels Long Creek (0-3) 7 p.m., Dragon Stadium First meeting

Navarro (2-0) vs. La Vernia (2-1) 7 p.m., Bear Stadium La Vernia leads series 14-2 Most recent meeting: 2025, La Vernia: 23-7 Last win for Navarro: 2021 (35-6)

Medina Valley Creek View (1-2) vs. Pearsall (1-1) 7 p.m., Mack Laxson Field First meeting

Pleasanton (2-1) vs. Beeville Jones (0-3) 7 p.m., Beeville Memorial Stadium Pleasanton leads series 16-11 Most recent meeting: 2023, Pleasanton: 21-14 Last win for Beeville Jones: 2019 (37-26)

Memorial (0-3) vs. Kennedy (0-2) 7 p.m., Edgewood Stadium Kennedy leads series 42-16 Most recent meeting: 2025, Kennedy: 49-21 Last win for Memorial: 2023 (20-6)

Uvalde (2-1) vs. Marion (2-1) 7 p.m., Veterans Stadium First meeting

Buda Johnson (1-2) vs. Alamo Heights (3-0) 7:30 p.m., Orem Stadium Alamo Heights leads series 1-0 Most recent meeting: 2020, Alamo Heights: 2020 Last win for Buda Johnson: None

Brennan (2-1, 1-0) vs. Sotomayor (2-1, 1-0) 7 p.m., Farris Stadium Brennan leads series 4-0 Most recent meeting: 2025, Brennan: 56-0 Last win for Sotomayor: None