Eagles rule out RB Saquon Barkley (hamstring), WR DeVonta Smith (hamstring) good to go for Week 6 vs. Panthers

The Philadelphia Eagles will be without running back Saquon Barkley for the second straight week, but will get wide receiver DeVonta Smith back after a two-game absence.

Barkley will sit out against the Carolina Panthers due to a hamstring injury. After exiting four snaps into Week 4, the running back sat out last week's loss to the Jacksonville Jaguars in London.

Smith has not played since Week 3, missing the past two games with his own hamstring issue. He had no injury designation on the Friday injury report.

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Smith took part in Friday's practice and told reporters afterward he felt "good" and that the decision on his availability for Sunday will be "up to the doctors."

Fellow Eagles wide receiver Dontayvion Wicks was a full participant in practice. He is dealing with a hamstring injury and was limited Wednesday before being held out of practice on Thursday. He returned to the field on Friday.

The Eagles will already be without quarterback Jalen Hurts after doctors found a superficial blood clot in his leg . Tanner McKee is in line to start at QB, though the Eagles signed QB Joe Milton on Friday from the Cowboys practice squad.

After this week, the 2-3 Eagles have three straight games against NFC East rivals beginning next Monday night against the Dallas Cowboys, followed by a Sunday night meeting with the Washington Commanders in Week 8 before returning home to take on the New York Giants. They will take their bye in Week 10.