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Democrat Annie Andrews defeats GOP Sen. Darline Graham in South Carolina, a major upset

NBC News projects that Graham failed to secure a full term after she was appointed to the seat held by her late brother.

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U.S. Sen.-elect Annie Andrews, D-S.C., speaks during an election night watch party at the Charleston Marriott on November 03, 2026 in Charleston, S.C.
U.S. Sen.-elect Annie Andrews, D-S.C., speaks during an election night watch party at the Charleston Marriott on November 03, 2026 in Charleston, S.C.

Democrats notched an upset victory in South Carolina’s Senate race, NBC News projects, with Annie Andrews toppling Republican Sen. Darline Graham, who was appointed this year to succeed her late brother, longtime Sen. Lindsey Graham. Andrews, a pediatrician, will be the state’s first Democratic senator in more than 20 years. President Donald Trump carried South Carolina by more than 17 percentage points two years ago. Gov. Henry McMaster appointed Darline Graham, a former administrator in state government, in July after Lindsey Graham, a five-term senator and stalwart fixture of Washington, died suddenly because of a heart problem. Follow live updates on the midterm elections Darline Graham then decided to run for a full term, starting in a special primary election, but she soon drew criticism for lacking fluency on some policy issues. She admitted in a debate with a Republican rival that she was “not that informed on national security,” though she went on to win the GOP nomination. Although the race was seen as a long shot for Democrats, Graham’s weaknesses prompted the Cook Political Report to shift it in September from “solidly” Republican to “likely” Republican. Meanwhile, Andrews significantly outraised and outspent Graham, who had to start her campaign from scratch mid-election cycle. In the final pre-election fundraising period, Andrews’ campaign raised more than $4 million, mostly from online donors, and spent over $4.6 million in two weeks. Graham’s campaign raised about $90,000 and spent $65,000. The race attracted a surge in outside spending in the closing stretch. The Senate Leadership Fund, a GOP super PAC, spent $13 million to boost Graham, while the Senate Majority PAC, which is aligned with Democratic leadership, announced a last-minute $750,000 digital buy. Andrews and Graham traded barbs in a debate last month, with Graham accusing Andrews of being unwilling to “stand up to socialist Democrats,” while Andrews said Graham was little more than a rubber stamp for Trump’s agenda. Andrews said she supported the Second Amendment — but Graham noted that Andrews has been a senior adviser to Everytown, the prominent gun control advocacy group. Andrews has also been accused of backpedaling on previous language signaling emphatic support for transgender people. Graham said Andrews has been “deceiving the people of South Carolina” and has “flip-flopped on everything.” Graham also made a notable break from Trump last month after he announced he would waive sanctions against Russia, going around a new law that was named for her brother. “Personally, I would choose to put the pressure on Russia to end the war and get gas prices down,” Graham told reporters at a campaign event. “Because I don’t trust Putin, and I don’t trust Russia.” Her remarks came even as Trump was scheduled to appear at a campaign stop for her in the state.

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Wednesday, November 4, 2026

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