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College football scores, live updates: Ohio State vs. Iowa, Florida vs. Missouri and more

We are through the first month of the season and there are several intriguing conference matchups on this week's slate.

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The first weekend of October has three matchups between ranked teams and a host of other intriguing college football games.It all started early in the SEC as No. 7 Alabama went into Starkville and throttled No. 16 Mississippi State in a 56-23 blowout. Kamario Taylor and the Bulldogs turned the ball over four times and the Crimson Tide may them pay for it. Alabama QB Keelon Russell finished with over 300 yards and four touchdowns in the win.In the afternoon window, all eyes will shift to a Big Ten clash between No. 5 Ohio State and No. 15 Iowa. The Hawkeyes are coming off a last-gasp road thriller at Michigan a week ago and have the best scoring defense in the country, but they'll have their hands full with Julian Sayin, Jeremiah Smith and the Buckeyes' offense. Also in the afternoon is an SEC matchup between No. 8 Florida and No. 25 Missouri.The marquee matchup on Saturday night is an ACC clash between No. 4 Miami and Clemson. Will Darian Mensah continue his torrid run early this season, or will the Tigers clamp down on the talented QB?Follow all of the action with live updates, highlights and analysis below:

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Saturday, October 3, 2026

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