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College football live updates, scores: Ohio State vs. Indiana, Mississippi State vs. LSU and more

With two top-10 matchups and a host of other good games, Week 7 is absolutely loaded.

· 180 words

Welcome to the biggest weekend of the 2026 college football season. So far, anyway. Week 7 features two games between top-10 teams and six games between teams ranked in the AP Top 25. It all starts with a Big Ten gem in the morning as defending champion Indiana takes on Ohio State in a clash of top-five teams. The Hoosiers haven't lost since Dec. 20, 2024; will the Buckeyes be the team that stops their winning streak at 22 games?In the afternoon, the SEC takes center stage as No. 6 Alabama faces No. 14 Tennessee and No. 13 Missouri meets No. 9 Ole Miss. All four teams already have a loss this year, so another one on Saturday could put CFP hopes on the brink and send their season into a spiral.In the evening marquee, No. 2 Notre Dame heads to Provo, Utah, to face No. 8 BYU. But there are several other worthwhile matchups to keep an eye on as well, including No. 18 Oklahoma State vs. No. 20 Houston.Follow along below on Saturday for highlights, analysis and more:

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Saturday, October 17, 2026

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